A Path-Distance Model Explains the Structure of the Genetic Code
A summary is provided of the main features of code evolution revealed by the path-distance model. They illustrate the dependence of code structure on amino acid path-distance. A mechanism is identified for coordinating code evolution with the growh of amino acid synthesis pathways. It is based on evidence of an early reliance on bifunctional tRNA that served as cofactors in amino acid synthesis and adaptors in translation.
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